Quetiapine in Prevention of Delirium

Ain Shams University

Status and phase: Completed; Phase 2

Conditions: Delirium

Treatments: Drug: Quetiapine

Study type: Interventional

Funder types: Other

Identifiers

NCT05793632

Quetiapine

Details and patient eligibility

About

The aim is to study the effectiveness of Quetiapine in preventing delirium in the elderly patients with multiple risks for delirium.

Enrollment: 90 patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with anemia
• Sedated patients
• Hypotensive patients
• Immobilized patients
• Patients with visual or auditory impairment

Exclusion criteria

• Patients or guardians refuse to participate
• Patients diagnosed with delirium
• Contraindication for delirium

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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90 participants in 2 patient groups

Quetiapine

Experimental group

Description:

The patients with multiple risks for delirium will receive 25 mg/day PO

Treatment:

Drug: Quetiapine

Non pharmacological preventive bundle

No Intervention group

Description:

The patients will only be monitored with application of delirium preventive bundle without pharmacological agent