Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV

Boston Medical Center (BMC)

Status: Completed

Conditions: HIV Infections; Smoking Cessation

Treatments: Other: Cell phone messages; Other: Self-help guide for quitting smoking; Other: Offered nicotine replacement therapy; Behavioral: Sessions with a trained counselor

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT05020899

H-41807

1R21CA243835-01A1 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this two arm randomized clinical trial (RCT) is to test if a smoking cessation program called Quit for Life (QFL) which was developed by the investigators is effective for patients in China with HIV who smoke. This program is designed to suit the needs of people with HIV who smoke in China.

Eligible participants who provide consent will be randomized into either the QFL or the Control group.

The QFL group will receive a quit smoking program that lasts for 8 weeks with two parts-

1. 4 sessions with a trained counselor who will discuss the participants' smoking habits and strategies to help them quit.
2. Messages sent to the participants' cell phone using WeChat.

The Control group will not have sessions with a trained counselor or receive messages sent to their cell phone.

Both groups will be offered nicotine replacement therapy and a self-help guide with information about quitting smoking.

Enrollment: 109 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HIV seropositive (by being at the HIV clinic and receiving care)
• Receiving ART treatment from the clinic (by being at the HIV clinic and receiving care)
• Smokes ≥ 5 cigarettes per day
• Able to speak and read in Mandarin Chinese
• Self-reported anticipate to receive ART treatment from the clinic for at least 9 months
• Own a cell phone
• Be willing to set a quit date within 1 month after baseline assessment

Exclusion criteria

• Self-reported using other smoking cessation program or medication
• Having a serious health problem that may make them unsuitable to stay in the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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109 participants in 2 patient groups

Quit for Life group

Experimental group

Description:

Participants randomized to this arm will receive a 8 week quit smoking program delivered by trained counselors and messages to their cell phones. Participants will also be offered nicotine replacement therapy (gum or patch, depending on which one is available) and a self-help guide with information about quitting smoking.

Treatment:

Behavioral: Sessions with a trained counselor

Other: Offered nicotine replacement therapy

Other: Self-help guide for quitting smoking

Other: Cell phone messages

Control group

Active Comparator group

Description:

Participants randomized to this arm will be offered nicotine replacement therapy (gum or patch, depending on which one is available) and a self-help guide with information about quitting smoking.

Treatment:

Other: Offered nicotine replacement therapy

Other: Self-help guide for quitting smoking