Rabeprazole Specific Clinical Experience Investigation for the Long-term Combination Therapy With Low-dose Aspirin

Eisai

Status: Completed

Conditions: Gastric Ulcer; Duodenal Ulcer

Treatments: Other: No Intervention

Study type: Observational

Funder types: Industry

Identifiers

NCT02423187

PRT12T

Details and patient eligibility

About

To investigate the safety and efficacy of long-term combination therapy with rabeprazole and low-dose aspirin.

Enrollment: 1,568 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients taking long-term low-dose aspirin for prevention of thrombus/embolism at the start of administration of rabeprazole (including patients who start low-dose aspirin on the same day as the start of administration of rabeprazole).
2. Patients with a history of gastric/duodenal ulcers.
3. Patients requiring long-term use of rabeprazole for prevention of recurrence of gastric/duodenal ulcers induced by low-dose aspirin.

Exclusion criteria

1. Patients with gastric/duodenal ulcers at the start of administration of rabeprazole.
2. Patients with active upper gastrointestinal bleeding at the start of administration of rabeprazole.
3. Patients with contraindication for rabeprazole.

Trial design

1,568 participants in 1 patient group

Arm 1

Description:

Participants with combination therapy (rabeprazole and low-dose aspirin)

Treatment:

Other: No Intervention