Racial Differences: Nitric Oxide(NO) and Endothelin-1(ET-1) in Preeclampsia (PreE)

University of Mississippi

Status: Completed

Conditions: Preeclampsia

Study type: Observational

Funder types: Other

Identifiers

NCT00653809

2007-0065

Details and patient eligibility

About

The goal of this study is to examine the activation of markers of endothelial and cardiovascular dysfunctions, from women with high-risk pregnancies. Information from this study will hopefully provide enough information to determine a link between race, the advent of high risk pregnancies and cardiovascular markers. With this information it might be possible to intervene with approved pharmacological treatments.

Enrollment: 52 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• African-american or Caucasian
• Pregnant
• Between ages of 18 - 40 years of age

Exclusion criteria

• Presence of a disease or condition which is not preeclampsia
• Drug or alcohol abuse during pregnancy
• Obesity

Trial design

52 participants in 8 patient groups

A, 1, I

Description:

Caucasian women without preeclampsia or PIH, delivering their first child

A, 1, II

Description:

Caucasian women with preeclampsia or PIH, delivering their first child

A, 2, I

Description:

African-american women without preeclampsia or PIH, delivering their first child

A, 2, II

Description:

African-American women with preeclampsia or PIH, delivering their first child

B, 1, I

Description:

Caucasian women without preeclampsia or PIH, delivering at least their second child

B, 1, II

Description:

Caucasian women with preeclampsia or PIH, delivering at least their second child

B, 2, I

Description:

African-american women without preeclampsia or PIH, delivering at least their second child

B, 2, II

Description:

African-american women with preeclampsia or PIH, delivering at least their second child