Radiochemotherapy in Elderly Patients With Oesophagus Cancer (Chronos)

Centre Hospitalier Universitaire de Besancon

Status and phase: Completed; Phase 2

Conditions: Esophagus Cancer

Treatments: Drug: Oxaliplatin; Drug: Cisplatin

Study type: Interventional

Funder types: Other

Identifiers

NCT02879227

P/2009/79

Details and patient eligibility

About

Phase II study of radiochemotherapy for elderly patients with oesophagus cancer.

Full description

Phase II study of radiochemotherapy for elderly patients with oesophagus cancer with Radiotherapy = 50 Gy, 2Gy/f ans chemotherapy with 2 arms arm Cisplatin = Cisplatin 75mg/m2 J1J22 or arm Oxaliplatine = oxaliplatine 85mg/m2 every 2 weeks.

Enrollment: 23 patients

Sex: All

Ages: 75+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients aged 75 or more with oesophagus cancer (squamous or adenocarcinoma), fit to treat

Exclusion criteria

• previous radiotherapy
• no fit to treat

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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23 participants in 2 patient groups

Arm Cisplatin

Active Comparator group

Description:

Radiotherapy 50 Gy with cisplatin 75 mg/2 Day 1 and day 22 (2)

Treatment:

Drug: Cisplatin

Arm Oxaliplatin

Experimental group

Description:

Radiotherapy 50Gy Oxaliplatin 85mg/m2 every 2 weeks, (6)

Treatment:

Drug: Oxaliplatin