Radiocontrast Media Induced Hyponatremia

Gachon University Gil Medical Center

Status: Unknown

Conditions: Percutaneous Coronary Intervention

Study type: Observational

Funder types: Other

Identifiers

NCT01219270

Hyponatremia-GUGH

Details and patient eligibility

About

Osmolality of contrast media can be resulted in translocational hyponatremia after percutaneous coronary intervention.

Full description

Radiocontrast media after percutaneous coronary interventioncan lead to increased osmolaliry of plasma, which results in translocational hyponatremia.

The investigator will exam the incidence of hyponatremia after percutaneous coronary intervention, and will evaluate the underlying mechanism related to hyponatremia including translocational hyponatremia, or osmotic natriuresis.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients who receive contrast media during percutaneous coronary intervention

Exclusion criteria

• Patients who have sensitivity to contrast media.
• Liver cirrhosis
• Hypothyroidism
• SIADH
• Patients who receive IVIG or mannitol.

Trial design

100 participants in 2 patient groups

GFR >= 60

Description:

MDRD eGFR 60 or more

GFR <60

Description:

Under MDRD eGFR 60