Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma With No-touch Technique

Seoul National University

Status: Completed

Conditions: Radiofrequency Ablation; Hepatocellular Carcinoma

Treatments: Procedure: RFA

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT03375281

SNUH-2017-0870

Details and patient eligibility

About

The aim of this study is to evaluate clinical outcome of RFA for small single nodular HCC using no touch technique with separable clustered electrode (Octopus) in a prospective multicenter manner Participating center: Seoul national university hospital, Asan medical center, Samsung medical center, Kunkuk university hospital, St. mary's Seoul hospital

Enrollment: 140 patients

Sex: All

Ages: 20 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Child-Pugh class A liver function
• 1 - 2.5 cm sized Single nodular HCC
• without history of previous HCC treatment or with evidence of no recurrence at least 2 years after previous HCC treatment

Exclusion criteria

• more than 2 HCC
• tumor size larger than 2.5 cm
• Child-Pugh class B or C liver function
• invisible tumor even after real-time fusion US guidance
• accompanied by vascular invasion or distant metastasis
• presence of coagulopathy defined as platelet count < 50,000/mm3 and/or PT-INR > 50%

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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140 participants in 1 patient group

No touch group

Experimental group

Description:

RFA for small HCC would be done by using no touch technique

Treatment:

Procedure: RFA