Radiofrequency-assisted Liver Resection in Intractable Liver Cancer

H

Hepatopancreatobiliary Surgery Institute of Gansu Province

Status

Completed

Conditions

Liver Cancer

Treatments

Procedure: TACE+radiofrequency
Procedure: TACE
Procedure: radiofrequency

Study type

Observational

Funder types

Other

Identifiers

NCT04413526
radiofrequency liver resection

Details and patient eligibility

About

In this retrospective study, the investigators assessed the application of radiofrequency-assisted liver resection in intractable liver cancer resection, and plan to analysis the different factors.

Full description

The primary clinical treatment of liver cancer is surgical resection, although many integrated applications develop rapidly, surgery is still the best way to remove the tumour lesion. Traditional ways that have curative removed tumours in three methods, which are liver resection, liver transplantation and radiofrequency ablation (RFA). As for primary liver cancer, surgery, and RFA are both effective and safety, but for the complexity of end-stage liver cancer, surgical resection may not remove the tumours alone. Surgical resection with radiofrequency ablation therapy for intractable liver cancer is a kind of active plan. The therapy can eliminate the tumour, maximize the protection of patient liver tissue, reduce operation damage, reduce the incidence of complications, and improve patients quality of life after surgery.

Enrollment

199 patients

Sex

All

Ages

18 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Ultrasound-guided fine-needle aspiration pathology or postoperative pathology was confirmed to be liver cancer, no pathological results according to China 's 2017 version of the hepatocarcinoma (HCC) diagnosis and treatment specifications, in line with the standard clinical diagnosis of liver cancer
  • According to Barcelona Clinic Liver Cancer (BCLC) staging criteria, it is stage C (stage C: single tumour> 5 cm or more than three tumours, and at least one tumour> 3 cm, liver function Child-Pugh A or B, with lymph node metastasis or distant metastasis or portal vein or Venous liver trunk is invaded, penance Status (PST) score 1-2 points)

Exclusion criteria

  • HCC patients with other malignant tumours
  • Metastatic liver tumour
  • Patients with liver abscess
  • Patients with organ dysfunction

Trial design

199 participants in 3 patient groups

radiofrequency-assisted liver resection
Description:
radiofrequency-assisted liver resection for intractable liver cancer
Treatment:
Procedure: radiofrequency
TACE(transcatheter arterial chemoembolization)
Description:
temporary TACE for intractable liver cancer
Treatment:
Procedure: TACE
radiofrequency ablation plus TACE
Description:
radiofrequency ablation plus TACE for intractable liver cancer
Treatment:
Procedure: TACE+radiofrequency

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems