Radiofrequency Catheter Ablation for Chronic Atrial Fibrillation

University of Michigan

Status: Completed

Conditions: Atrial Fibrillation

Treatments: Drug: Amiodarone and cardioversion; Procedure: Radiofrequency catheter ablation

Study type: Interventional

Funder types: Other

Identifiers

NCT00272636

2002-0480

Details and patient eligibility

About

The purpose of this study is to determine the long-term efficacy of radiofrequency catheter ablation in patients with chronic atrial fibrillation.

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chronic atrial fibrillation

Exclusion criteria

• Left atrial diameter >55 mm
• Left ventricular ejection fraction <0.30
• Contraindication to amiodarone therapy or anticoagulation with warfarin
• Presence of a mechanical prosthetic valve
• History of a cerebrovascular accident
• Presence of left atrial thrombus on TEE
• Prior attempt at catheter or surgical ablation for atrial fibrillation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)