Radiologic Scoring of Patients With Chronic Sinusitis and Nasal Polyps

Assiut University

Status: Unknown

Conditions: Chronic Sinusitis

Treatments: Drug: Hypertonic saline; Drug: Fluticasone Nasal

Study type: Interventional

Funder types: Other

Identifiers

NCT03174483

HSCS

Details and patient eligibility

About

To detect the effect of hypertonic saline and fluticasone sprays on computed tomography scan of paranasal sinuses of patients having chronic sinusitis and/or nasal polyps.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients with chronic sinusitis and/or nasal polyps.

Exclusion criteria

• Patients with previous nasal or sinus surgery.
• Patients with sinonasal Malignancy.
• Immunocompromised patients.
• Patients with ciliary motility disorders.
• Pregnant women

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

hypertonic saline

Experimental group

Description:

nasal spray will be used twice daily

Treatment:

Drug: Hypertonic saline

fluticasone

Active Comparator group

Description:

nasal spray will be used once daily

Treatment:

Drug: Fluticasone Nasal