Radiomics-based Models for the Prediction of Pathological Response to Neoadjuvant Therapy in Gastric and Gastroesophageal Cancer (RADI-S)

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Completed

Conditions: Patients With Locally Advanced Carcinoma of the Stomach and Oesophagogastric Junction

Treatments: Radiation: CT scan

Study type: Observational

Funder types: Other

Identifiers

NCT06044961

5297

Details and patient eligibility

About

Identifying predictors of response to neoadjuvant therapy in gastric and gastro-oesophageal cancer early in the history of the disease would ensure optimal treatment planning.

The study aims to apply radiomics for the prediction of response to neoadjuvant therapy.

Enrollment: 80 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with locally advanced stomach cancer undergoing neoadjuvant chemotherapy and gastrectomy between January 2005 and August 2022

Exclusion criteria

• Siewert 1 tumors;
• Patients who have received neoadjuvant with the addition of a biological drug;
• Patients who have received radiotherapy;
• Patients without staging CT scan or with insufficient image quality in terms of phases performed, pixel spacing, slide thickness (mandatorily: > 5 mm) or artefacts.