Radiotherapy in Palliation of Advanced Pelvic Cancer

Scientific Institute for Research Hospitalization and Healthcare (IRCCS)

Status: Completed

Conditions: Palliative Care

Treatments: Radiation: Short course radiotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT03947268

SHARON PELVIS (phase II trial)

Details and patient eligibility

About

The study wants to define the safety and efficacy of a short-course radiation therapy in patients with symptomatic advanced pelvic cancer.

Full description

he study wants to define the safety and efficacy of a short course accelerated radiation therapy delivered in twice daily fractions and 2 consecutive days for symptomatic palliation of advanced solid cancer.

Enrollment: 25 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• histologically proven advanced pelvic cancer
• excluded from curative therapy because of disease stage and/or presence of multiple comorbidities and/or poor performance status
• age > 18 years
• Eastern Cooperative Oncology Group (ECOG) <3

Exclusion criteria

• prior radiotherapy to the same region

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

25 participants in 1 patient group

Short-course radiotherapy

Experimental group

Description:

The radiotherapy is delivered over 2 days with accelerated hypo-fractionation technique.

Treatment:

Radiation: Short course radiotherapy