Randomised, Controlled Trial of an Individual Deprescribing Intervention for Nursing Homes Residents (OLD-NH-IDeI)

Anne Niquille

Status: Completed

Conditions: Polypharmacy; Inappropriate Prescribing

Treatments: Other: Individual Deprescribing Intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT03655405

OLD-NH-IDeI-2018

Details and patient eligibility

About

This study will evaluate the effects of a pharmacist-led, deprescribing-focused medication review on the use of inappropriate medications by nursing home residents

Full description

Nursing home residents are often prescribed inappropriate medication, drugs whose negative effects outweigh potential benefits or which are not useful anymore. Inappropriate medication have been linked with worse health outcomes, hospitalisations and death. Deprescribing, the structured process of withdrawing or tapering inappropriate medications, has been studied as a potential solution to this problem.

In this study, nursing home residents living in institution which are already engaged in a deprescribing process will be randomly allocated to receive a medication review or usual care. The medication review will be performed by the nursing home pharmacist an its results will be discussed with the responsible physicians and nurses to create a deprescribing plan specifically tailored to the needs of the resident.

Enrollment: 62 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Take 5 or more prescribed drugs daily;
• Reside in the Nursing Home since at least 4 months.

Exclusion criteria

• Physician judges that discussing deprescribing with them risks destabilising them.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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62 participants in 2 patient groups

Individual Deprescribing Intervention

Experimental group

Description:

Participants allocated to the intervention arm will receive the Individual Deprescribing Intervention (pharmacist-led medication review, followed by the creation of a deprescribing plan by the pharmacist, physician and responsible nurse).

Treatment:

Other: Individual Deprescribing Intervention

Control

No Intervention group

Description:

Participants allocated to the control group will receive usual care.