Randomised Exposure Study of Pollution Indoors and Respiratory Effects (RESPIRE)

University of California (UC), Berkeley

Status

Completed

Conditions

Pneumonia

Respiratory Tract Infections

Treatments

Device: Plancha

Study type

Interventional

Funder types

Other

Identifiers

NCT01047696

R01ES010178 (U.S. NIH Grant/Contract)

2003-8-165

Details and patient eligibility

About

The purpose of this study was to determine whether reduced exposure to indoor air pollution would reduce ALRI incidence in children <18 months of age. Households were randomized to receive a chimney stove (intervention group) or continue using an open fire for cooking and heating (control group).

Full description

Acute lower respiratory infections (ALRI) are the chief killer of children. Most cases are pneumonia and the majority occur among poor children under five years in developing countries. Poverty might be said to be the primary cause, which manifests as malnutrition, including micro-nutrient deficiencies, and lack of access to medical care. Another attribute of poverty is household indoor air pollution (HAP) from use of unprocessed solid fuels such as biomass (wood, animal dung and crop wastes) and coal in simple stoves. A meta-analysis of published observational studies found that young children exposed to smoke from household solid fuel use had a rate of ALRI twice that of children not exposed or where clean fuels were used. Recent studies have shown similar ALRI risks associated with short-term air pollution measurements and other indicators of exposure.

Enrollment

537 patients

Sex

All

Ages

Under 18 months old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Households were invited to participate in the study if they met the following inclusion criteria:

Used only an open fire for cooking and heating
Had a pregnant woman or child < 4 months residing in the home
Identified as Mam (the regional ethnic group), and had
Minimal summer migration (less than 12 weeks per year)

Exclusion criteria

Households were excluded from participating if:

The household was already using a chimney stove for cooking
There was no child <4 months of age or a pregnant woman residing in the home
Seasonal migration required the family to move to another region for more than 12 weeks of the year