Randomized Assessment of Rapid Endovascular Treatment in Basilar Artery Occlusion Stroke in 115 Hospital (RARETBAS)

University of Medicine and Pharmacy at Ho Chi Minh City

Status: Unknown

Conditions: Basilar Artery Occlusion; Stroke, Acute

Treatments: Procedure: Thromboectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT04177615

yds2019

Details and patient eligibility

About

This is a prospective, open lable studies conducted in 115 hospital to compare between thromboectomy and Recombinant Tisue Plasminogen Activator only to evaluate the eficacy and safety of endovascular treatment in basilar artery occlusion stroke patients

Full description

Acute basilar artery thrombosis is associated with a poor prognosis. Prevalence of basilar artery occlusion are not known. Although basilar artery occlusion has been reported in 2 per 1000 autopsy cases, basilar artery thrombosis may, in stroke registries, explain as many as 27% of ischemic strokes occurring in the posterior circulation.Various treatments were tried in groups of patients with vertebrobasilar territory infarction but evidence based was not cleared previous studies. Therefore, we conduct this study to evaluate the eficacy and safety of endovascular treatment in basilar artery occlusion stroke patients

Enrollment: 109 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients admit to 115 hospital in 24h of Basilar Artery Occlusion Stroke
• NIHSS > 4 points

Exclusion criteria

• Patients refuse to participate in studies
• Patients with contraindication of either rTPA or thromboectomy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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109 participants in 2 patient groups

Thromboectomy and rTPA

Experimental group

Description:

use thromboectomy and rtpa for patient with basilar artery occlusion stroke in 24 hour

Treatment:

Procedure: Thromboectomy

rTPA( recombinant tissue plasminogen activator )

No Intervention group

Description:

use rtpa for patient with basilar artery occlusion stroke in 24 hour