Randomized Clinical and Radiographic Study

Tanta University

Status: Completed

Conditions: Autogenous Dentin Graft

Treatments: Procedure: (guided tissue regeneration)

Study type: Interventional

Funder types: Other

Identifiers

NCT06609720

OMPDR

Details and patient eligibility

About

Randomized clinical and radiographic trial

Full description

Evaluation of Autogenous Dentin Graft versus Demineralized Freeze-Dried Bone Allograft in the Treatment of Class ΙΙ and ΙΙΙ Mandibular Furcation Defects

Enrollment: 32 patients

Sex: All

Ages: 35 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Presence of class II and/or ΙΙΙ furcation defects in mandibular first or second molars according to criteria outlined by Hamp et. al. 1975.

• Horizontal probing depth ≥3 mm using Naber's probe.
• Clinical attachment level ≥3 mm measured from cemento-enamel junction (CEJ) till the deepest probing depth.
• Evidence of radiolucency in the furcation area on panoramic radiograph.
• Patients who will be assigned for groups (I and II) should present with teeth required for extraction due to advanced periodontal bone loss or other indications such as hopeless wisdom teeth or orthodontic indications or unrestorable fractured teeth as a source for autogenous dentin graft (ADG).

Exclusion criteria

• Medically compromised patients and systemic conditions precluding periodontal surgery.

  • Mandibular first or second molars with root caries or endodontic treatment.
  • Smokers, diabetics, pregnant or lactating women.
  • History of chemotherapy, radiotherapy in head and/or neck region.
  • Bisphosphonate therapy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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32 participants in 4 patient groups

Group 1 subgroup A

Experimental group

Description:

Grade II furcation involvement treated with autogenous dentin graft

Treatment:

Procedure: (guided tissue regeneration)

Group 1 Subgroup B

Experimental group

Description:

Grade II furcation involvement treated with demineralized freeze-dried bone allograft

Treatment:

Procedure: (guided tissue regeneration)

Group II subgroup A

Experimental group

Description:

Grade III furcation involvement treated with Autogenous dentin graft

Treatment:

Procedure: (guided tissue regeneration)

Group II subgroup B

Experimental group

Description:

Grade III furcation involvement treated with demineralized freeze-dried bone allograft

Treatment:

Procedure: (guided tissue regeneration)