Randomized Clinical Trial for Comparison Of Intravenous Carbeitocin Versus Oxytocin In Management Of Placental Delivery In Second Trimester Interruption

Wafaa Uthman Ahmed

Status and phase: Unknown; Phase 4

Conditions: CARBETOCIN FOR PREVENTION OF PLACENTAL RETAINED

Treatments: Drug: oxytocin; Drug: Carbetocin

Study type: Interventional

Funder types: Other

Identifiers

NCT01827124

Ain Shams U

Details and patient eligibility

About

Intravenous Carbetocin is more efficient than intravenous infusion oxytocin in management of placental delivery in 2nd trimester interruption.

Enrollment: 140 estimated patients

Sex: Female

Ages: 16 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age:16-50 years
• Pregnancy duration: 14-24weeks
• Spontaneous abortion or medical induced abortion at 14-24weeks

Exclusion criteria

• Age less than 16years and more than 50 years
• Surgical termination
• Placenta previa
• Uterine fibroid

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Triple Blind

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140 participants in 2 patient groups

carbetocin and placebo

Experimental group

Description:

100microgram carbetocin IV and 1cc normal saline(placebo)infusion

Treatment:

Drug: Carbetocin

Drug: oxytocin

oxytocin and placebo

Experimental group

Description:

20Interntional unit oxytocin infusion and 1cc normal saline IV

Treatment:

Drug: Carbetocin

Drug: oxytocin