Randomized Controlled Trail of Polyethylene Glycol vs Sodium Phosphate for Colonic Cleansing of Colonoscopy

Dong Yang

Status and phase: Completed; Phase 4

Conditions: Sodium Phosphate; Polyethylene Glycol

Treatments: Drug: polyethylene glycol; Drug: sodium phosphate

Study type: Interventional

Funder types: Other

Identifiers

NCT03817788

130022

Details and patient eligibility

About

This study is to compare polyethylene glycol and sodium phosphate for colonic cleansing of colonoscopy.

Enrollment: 586 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Outpatients meet the following criteria: 1) age 18-60 years; 2) BMI 18.9-28; 3) Heart, lung, liver, and kidney function can tolerate colonoscopy; 4) Patients and their families are able to understand and be willing to participate in this clinical study and to sign informed consent

Exclusion criteria

• 1. colorectal surgery history (except appendectomy); 2) patients with intestinal obstruction, incomplete obstruction, intestinal hemorrhage; 3) patients with renal insufficiency; 4) patients with hirschsprung disease; 5) patients with inflammatory bowel disease during active period, which affects intestinal observation; 6) patients who are bedridden and lose the moving ability ; 7) have a history of severe mental illness; 8) pregnant or lactating women; 9) patients with other clinical conditions considered by some researchers should not participate in the trial.

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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586 participants in 2 patient groups

polyethylene glycol group (group P)

Active Comparator group

Description:

For all patients of this group, polyethylene glycol solution should be taken orally for colonic cleansing of colonoscopy

Treatment:

Drug: polyethylene glycol

sodium phosphate group (group S)

Experimental group

Description:

For all patients of this group, sodium phosphate solution should be taken orally for colonic cleansing of colonoscopy

Treatment:

Drug: sodium phosphate