Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients

National Institutes of Health (NIH)

Status: Completed

Conditions: Parkinson Disease

Treatments: Drug: Glucose

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00004451

199/13548

K07MH001197 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study will determine whether glucose facilitates memory in healthy elderly people and those with Parkinson's disease.

Full description

Subjects fast for 8 hours before receiving a test to determine their blood glucose levels. Following this test, subjects are randomized to receive either a glucose or saccharin sweetened drink. A series of memory tests and an additional 3 blood glucose level tests are administered approximately 15 minutes later. A minimum of 1 week afterward, the subjects return and receive the alternate sweetener followed by additional memory tests.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Three groups of subjects are eligible for this study: Healthy young adults between ages 18 and 30; Healthy elderly adults between ages 60 and 90; AND Anyone diagnosed with Parkinson's disease

Exclusion criteria

• Prior surgery to remove part of the stomach
• Diabetes, Addison's, or Cushing's diseases