Randomized Study on Salt Intake and Energy Metabolism (TS4)

Charité University Medicine Berlin

Status: Completed

Conditions: Healthy

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Salt

Study type: Interventional

Funder types: Other

Identifiers

NCT03024567

Tissue Salt 4

Details and patient eligibility

About

To perform a randomized, double-blind clinical study on the effects of an increased salt intake on metabolic, cardiovascular and immunological parameters and the gut microbiota

Enrollment: 40 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy men and women
• 18 - 50 years
• Body mass index 18.5 - 29.9 kg/m2

Exclusion criteria

• Clinically relevant heart, lung, liver, and kidney diseases
• Current or chronic infection
• Habitual use of probiotics or dietary supplements
• Pregnancy, lactation

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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40 participants in 2 patient groups, including a placebo group

Salt

Active Comparator group

Description:

6 grams sodium chloride per day for 14 days

Treatment:

Dietary Supplement: Salt

Placebo

Placebo Comparator group

Description:

6 grams gelatine per day for 14 days

Treatment:

Dietary Supplement: Placebo