Randomized Trial of Prolonged Exposure for the Treatment of Posttraumatic Stress Disorder (PTSD)

University of Puerto Rico (UPR)

Status: Completed

Conditions: Posttraumatic Stress Disorder

Treatments: Behavioral: Prolonged Exposure; Behavioral: Applied Relaxation

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT02134691

SC1MH090599

Details and patient eligibility

About

This project will examine the impact of PE therapy for the treatment of PTSD with a sample of Latinos. The need to provide effective treatment to Spanish-speaking Latinos with PTSD is critical given the high prevalence of PTSD among Latinos. Furthermore, PTSD remains an under detected and under treated condition. Untreated PTSD has a substantial impact on health, functioning and quality of life. PE is one of the most empirically supported psychological interventions for PTSD. However, most studies that evidence the efficacy of PE have been conducted mainly with English-speaking Caucasian populations. This study has the potential to contribute to improvements in the well-being of Spanish-speaking Latinos with PTSD.

Enrollment: 98 patients

Sex: All

Ages: 18 to 64 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 to < 65 years
• Meet diagnostic criteria for PTSD
• Spanish speaker
• Allow recording of assessments and therapy

Exclusion criteria

• Significant current suicidal or homicidal ideation
• History of bipolar, schizophrenia or psychotic disorder
• Alcohol or drug abuse during the past three months
• Current high risk of being assaulted (i.e., living with domestic violence)
• Current psychotherapy to treat PTSD
• Unable to provide informed consent

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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98 participants in 2 patient groups

Prolonged Exposure

Experimental group

Description:

Behavioral: Prolonged Exposure (PE) PE is a 16 week, 90 minute culturally informed treatment program.

Treatment:

Behavioral: Prolonged Exposure

Applied Relaxation

Active Comparator group

Description:

Behavioral: Applied Relaxation (AR) AR is a 16 week, 90 minute treatment program.

Treatment:

Behavioral: Applied Relaxation