Rapid Non-Invasive Brain Stimulation for Hoarding Disorder (TMS-HOLA)

Stanford University

Status: Not yet enrolling

Conditions: Hoarding Disorder; Clutter; Hoarding

Treatments: Device: MagPro X100 by MagVenture

Study type: Interventional

Funder types: Other

Identifiers

NCT06712914

77098

Details and patient eligibility

About

This study explores whether rapid non-invasive brain stimulation can help reduce hoarding disorder symptoms.

Full description

Hoarding disorder (HD) is characterized by difficulty letting go of possessions, leading to clutter that congests living spaces and impairs daily functioning. The majority of HD patients treated with cognitive behavioral therapy for HD usually experience considerable residual symptoms. New treatments are greatly needed. This study explores whether rapid non-invasive brain stimulation can help reduce hoarding disorder symptoms.

Enrollment: 10 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age 18-70 years
2. Primary diagnosis of hoarding disorder
3. Sufficient severity of hoarding symptoms
4. Willing and able to understand and complete consent and study procedures

Exclusion criteria

1. Psychiatric or medical conditions or medications that make participation unsafe
2. Pregnant or nursing females
3. Previous exposure to TMS or ECT
4. History of any implanted device or psychosurgery

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Theta-burst stimulation (TBS)

Experimental group

Description:

Theta-burst stimulation (a form of transcranial magnetic stimulation) targeting the right frontal pole.

Treatment:

Device: MagPro X100 by MagVenture