Rapid Ventricular Pacing in Surgical Treatment of Intracranial Aneurysms

University Clinic Frankfurt

Status: Unknown

Conditions: Intracranial Aneurysm; Surgical Clip

Treatments: Procedure: Rapid Ventricular Pacing

Study type: Interventional

Funder types: Other

Identifiers

NCT02766972

497/13

Details and patient eligibility

About

Treatment of complex unruptured intracranial aneurysms (UIA) remains challenging to date. Therefore, advanced techniques are required to achieve an optimal result in treating these patients safely. In this study, the safety and efficacy of rapid ventricular pacing (RVP) to facilitate microsurgical clip-reconstruction has been studied prospectively in a joined neurosurgical, anesthesiological and cardiological study.

Full description

Treatment of complex unruptured intracranial aneurysms (UIA) remains challenging to date. Therefore, advanced techniques are required to achieve an optimal result in treating these patients safely. In this study, the safety and efficacy of rapid ventricular pacing (RVP) to facilitate microsurgical clip-reconstruction has been studied prospectively in a joined neurosurgical, anesthesiological and cardiological study. Patients with complex UIA were prospectively enrolled and the safety and efficacy of RVP were evaluated recording cardiovascular events and outcome of the patients as well as the amount of aneurysm occlusion after the surgical clip-reconstruction procedure.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• complex UIA intended to be treated by microsurgical clip-reconstruction
• application of RVP intra-operatively

Exclusion criteria

• structural heart disease or conductance abnormalities

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 1 patient group

RVP

Experimental group

Treatment:

Procedure: Rapid Ventricular Pacing