Rapid Versus Slow Ingestion of Mixed Meal: Influence on Islet and Incretin Hormone Secretion in Healthy Volunteers

Lund University

Status: Completed

Conditions: Healthy Volunteers Recruited From the General Population

Treatments: Other: Mixed meal

Study type: Interventional

Funder types: Other

Identifiers

NCT01779622

17

2013-000449-38 (EudraCT Number)

Details and patient eligibility

About

To test the influence of rapid versus slow ingestion of a mixed meal on insulin and incretin hormone secretion in healthy volunteers

Full description

A mixed meal (524 kcal) is ingested rapidly (within 5 min) or slowly (10-15 min) and changes in insulin, glucagon, GIP and GLP-1 levels are followed for subsequent 300 min

Enrollment: 24 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy subjects

Exclusion criteria

• Diabetes Liver disease Kidney disease Thyroid disease

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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24 participants in 1 patient group

1

Experimental group

Description:

Healthy volunteers are ingesting a mixed meal either rapidly or slowly

Treatment:

Other: Mixed meal