Rare and Undiagnosed Disease Research Biorepository (PRaUD)

Mayo Clinic

Status: Invitation-only

Conditions: Undiagnosed Disease; Rare Diseases

Treatments: Other: Genetic test evaluation

Study type: Observational

Funder types: Other

Identifiers

NCT04703179

19-003389

Details and patient eligibility

About

This research study is being done to find markers and identify causes of rare and undiagnosed diseases by analyzing patient's DNA (i.e., genetic material), RNA, plasma, urine, tissues, or other samples that could be informative of symptoms. Researchers are creating a biobank (library) of samples and information to learn more about treating rare and undiagnosed diseases.

Enrollment: 5,000 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Has Mayo Clinic or other medical health system ID, or another unique identifier
• Able to provide informed consent

Must meet one of the following:

• Individual must have evidence of a rare disease or a suspected genetic disorder as determined by a provider or genetic counselor
• Biological family member of an enrolled individual

Exclusion criteria

• Individuals who have situations that would limit compliance with the study requirements
• Institutionalized (i.e. Federal Medical Prison)