Raspberry Ketone Intake Upregulates Circulating FGF21 and Induces Energy Expenditure in Humans

Nanchang University

Status and phase: Completed; Early Phase 1

Conditions: Diabetes; NAFLD (Nonalcoholic Fatty Liver Disease); Obesity

Treatments: Dietary Supplement: Raspberry ketone

Study type: Interventional

Funder types: Other

Identifiers

NCT06681597

I-MRER [2023] No. 68

Details and patient eligibility

About

To investigate the molecular mechanism of raspberry ketone on regulating obesity, the investigators studied the effect of raspberry ketone intake on FGF21 in plasma.

The age of the volunteers were 18-60 years old, both male and female, without diabetes, hypertension and other diseases.

After ingestion of raspberry ketone (500mg), 2ml of blood was collected at 0 hours, 3 hours and 6 hours , and the FGF21 content in plasma was measured using a commercial reagent kit.

In addition, the investigators also studied the effect of raspberry ketone intake on energy metabolism 0 hours, 0.5 hours, 3 hours and 6 hours after consuming raspberry ketone (500mg).

Enrollment: 60 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

No drugs were taken before the human study

Exclusion criteria

Patients with hypertension

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Human administrated with raspberry ketone

Experimental group

Treatment:

Dietary Supplement: Raspberry ketone

Human administrated with placebo

Experimental group

Treatment:

Dietary Supplement: Raspberry ketone