Aromatherapy in Reducing PONV for Total Joint Replacement Patients (RCT PONV)

Hong Kong Buddhist Hospital

Status: Enrolling

Conditions: Postoperative Nausea and Vomiting; Total Joint Replacement Surgery

Treatments: Other: Placebo Patches; Other: Aromatherapy patches; Drug: Control (Standard treatment)

Study type: Interventional

Funder types: Other

Identifiers

NCT07281885

CIRB-2025-242-5

Details and patient eligibility

About

This study investigates the effectiveness of aromatherapy in reducing postoperative nausea and vomiting (PONV) among patients undergoing total joint replacement surgery, as these complications can lead to patient discomfort and prolonged recovery. It is designed as a randomized controlled trial involving 159 participants, who will be divided into three groups: an intervention group receiving aromatherapy patches (lavender-sandalwood or orange-ginger) plus standard care, a placebo group with a placebo patch plus standard care, and a control group receiving standard care alone. PONV will be measured using the Rhodes Index of Nausea, Vomiting, and Retching (RINVR) at baseline, 30 minutes after the intervention, and every 12 hours post-surgery. Additionally, patient satisfaction will be assessed through a 5-point Likert scale survey. The primary outcome of the study is the evaluation of RINVR scores, while the secondary outcome focuses on patient satisfaction levels. Data will be statistically analyzed using two-way ANOVA for repeated measures, with a significance level defined as p < 0.05. The study aims to determine the viability of aromatherapy as a complementary treatment for PONV, potentially improving postoperative care, enhancing patient satisfaction, and offering a cost-effective alternative to conventional anti emetic treatments if proven effective.

Enrollment: 159 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged 18 or above
• Patients scheduled for total joint replacement surgery at the HKBH

Exclusion criteria

• Cognitive impairments
• Allergy to lavender, orange, ginger, or sandalwood
• Allergy to micro-pore tape
• Allergy to opioid medication
• Undergoing other therapeutic treatment for PONV control, except prescribed medications

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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159 participants in 3 patient groups, including a placebo group

Aromatherapy patches

Experimental group

Description:

Standard Care + Use of Aromatherapy Patches

Treatment:

Other: Aromatherapy patches

Placebo patches

Placebo Comparator group

Description:

Standard Care + Use of Placebo Patches

Treatment:

Other: Placebo Patches

Prescribed antiemetic treatment

Active Comparator group

Description:

As standard care alone

Treatment:

Drug: Control (Standard treatment)