Re-Orchestration of Interregional Oscillatory Activity to Promote Visual Recovery (R4V)

Ecole Polytechnique Fédérale de Lausanne

Status: Active, not recruiting

Conditions: Stroke; Parkinson Disease; Visual Impairment

Treatments: Other: Cross-frequency dual-site tACS

Study type: Interventional

Funder types: Other

Identifiers

NCT05220449

2017-01761

Details and patient eligibility

About

This project assesses the effect of bifocal cross-frequency transcranial alternating current stimulation (tACS) combined with visual training to improve visual recovery and orchestrated oscillatory activity in stroke patients suffering from visual field defects.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. the patient can consent for themselves;
2. age 18+ years old;
3. at least 7 days since diagnosis "stroke".
4. Patients should demonstrate a clear deficit in either simple or complex visual perception in portions of their visual field

Exclusion criteria

1. Diminished capacity to consent;
2. Pregnancy
3. Known or suspected non-compliance, drug or alcohol abuse
4. Inability to follow the procedures of the study, e.g., due to language problems, psychological disorders, dementia, etc. of the participant,
5. Non-compliance to the instructions of the experimenter or an inappropriate behavior hindering the normal progress of the experiment.
6. Previous enrolment into the current study
7. Exclusion criteria of MRI, tACS, TMS
8. Use of psychoactive medication

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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30 participants in 2 patient groups

Cf-tACS (V1-Alpha_V5-Gamma)

Active Comparator group

Treatment:

Other: Cross-frequency dual-site tACS

Cf-tACS (V1-Gamma_V5-Alpha)

Experimental group

Treatment:

Other: Cross-frequency dual-site tACS