"Real-life" Cohort Study on Patients With Chronic HBV Infection in Jiangsu

Nanjing University

Status: Enrolling

Conditions: Hepatitis B， Chronic

Study type: Observational

Funder types: Other

Identifiers

NCT03097952

NJDTID-001

Details and patient eligibility

About

Hepatitis B virus (HBV) infection remains one of the most serious health problems worldwide. Patients with chronic HBV infection are at an increased risk for developing hepatic cirrhosis, hepatocellular carcinoma and even death. Although some predictive factors of the outcome of chronic HBV infection were identified, more precisely determine the factors which are associated with the outcome in non-selected patients with chronic HBV infection are still needed. The investigators purpose is to constitute a observational cohort of non-selected Chinese patients to create a database of epidemiological, clinical, biological, virological, immunologic and therapeutic parameters, in order to determine factors associated with the outcome of chronic HBV infection.

Enrollment: 20,000 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with chronic HBV infection (defined as HBsAg positive for at least 6 months)

Exclusion criteria

• Co-infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV) and/or hepatitis D virus (HDV)
• History of liver transplantation
• History of hepatocellular carcinoma (HCC)