Real-time Comparison of Left Ventricular Strokevolume Measurement by Four Different Methods (FourComp)

University Hospital, Linkoeping

Status: Completed

Conditions: Difference in Measured Results Using Four Different Strokevolume Measurements Simultaneously.

Treatments: Procedure: Arterial waveform analysis, esofageal doppler, transthoracal cardiac ultrasound, Cardiac magnetic resonance imaging.

Study type: Observational

Funder types: Other

Identifiers

NCT01791283

FourCompv1

Details and patient eligibility

About

Real-time comparison of three different bedside strokevolumemeasurements (arterial waveform analysis, eosofageal doppler and 2D transthoracal ultrasound) validated against cardiac magnetic resonance imaging (CMRI)

Full description

20 healthy volounteers between age of 20-40 years, no previous medical history undergo simoultaneous left ventrikular strokevolume measurements using three different methods at rest. After datasampling and without moving, the subject then undergo Cardiac Magnetic Resonance Imaging with 2D-throughplane and cine tecnology for validation of volume measurements. The data is then analyzed using Bland-Altman calculation.

Enrollment: 20 patients

Sex: All

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:Healthy volounteers age 20-40, BMI < 30, weight < 100 kg, no medications, sinus rythm on ECG, no contra-indications for MRI, ability to give written informed consent.

Exclusion Criteria:

• Heart and/or vascular disease such as angina pectoris, arrythmias, claudicatio intermittens e g.
• Diseases in gastrointestinal tract or nose.
• Coagulopathies
• Pregnancy
• Allergys for local anaesthetics
• Claustrofobia

Trial design

20 participants in 1 patient group

Healthy volunteers

Description:

Healthy volounteers with no previous medical history, age between 20-40. Both male and female. Subjects are provided extensive information about the study and the obligations and expectations included. All subjects sign a witnessed informed consent before inclusion.

Treatment:

Procedure: Arterial waveform analysis, esofageal doppler, transthoracal cardiac ultrasound, Cardiac magnetic resonance imaging.