Real-time Glaucoma Medication Adherence

University of Tennessee

Status: Terminated

Conditions: Glaucoma

Treatments: Behavioral: Medication reminder; Behavioral: Medication monitoring only

Study type: Interventional

Funder types: Other

Identifiers

NCT03194828

17-05074-XP

Details and patient eligibility

About

This study will evaluate the effectiveness of real-time data collected on patients taking topical medication to treat glaucoma. Patients will be randomized to two groups, the first of which will only use the study device to take their medication, while the second will use the study device and receive on-demand reminder messages, when necessary.

Full description

Adherence to topical medications to treat glaucoma remains sub optimal; however, our understanding of this behavior remains limited due to biased measures of medication use. The Kali Drop device is a potential improvement in our ability to capture medication use in patients using dropper bottles by precisely capturing the amount dispensed in real-time. Moreover, such technology creates data that can be leveraged into driving behavior change using connected mobile technology in order to improve adherence and, ultimately, health outcomes. While evidence suggests that reminders may improve adherence to glaucoma medications, the power of doing so using real-time data has yet to be explored. This study will compare simple monitoring of patients to those who are being monitored and who receive reminder messages when the system determines one is necessary due to a missed dose.

Enrollment: 5 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 years of age and older
• Glaucoma diagnosis
• Prescription for a prostaglandin indicated for glaucoma
• Nonadherent (MPR<80%) in the last 3 months according to pharmacy records
• Owns and operates a mobile phone and willing to receive periodic reminder messages

Exclusion criteria

• Existing chronic eye condition in addition to glaucoma
• Scheduled for eye surgery in the next 90 days
• Prescription for a medication that will not fit in the device
• Non-English speaking

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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5 participants in 2 patient groups

Monitoring only

Active Comparator group

Description:

Patients in this arm will be given a real-time medication use monitor to use in dispensing their topical glaucoma medication for 3 months

Treatment:

Behavioral: Medication monitoring only

Monitoring and reminder

Experimental group

Description:

Patients in this arm will be given a real-time medication use monitor to use in dispensing their topical glaucoma medication for 3 months and will receive an automated reminder (text or voice) when a missed dose is determined by the device's system

Treatment:

Behavioral: Medication reminder