Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury (RAPID-TBI)

University of Maryland Baltimore (UMB)

Status: Enrolling

Conditions: Traumatic Brain Injury

Study type: Observational

Funder types: Other

Identifiers

NCT05084352

HP-00087051

Details and patient eligibility

About

This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction scores regarding neuroworsening and other outcomes following traumatic brain injury.

Enrollment: 1,200 estimated patients

Sex: All

Ages: 18 to 79 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Arrival to the hospital within 6 hours of injury
• Age >= 18 years old
• Patients with traumatic brain injury(TBI). TBI is defined as any alteration or loss of consciousness with or without positive head C.T findings.

Exclusion criteria

• Deemed to have a non-survivable TBI
• Brain dead on arrival
• Active substance abuse for opiates and cocaine as noted by admission toxicology screen.
• Any thoracic or abdominal injury resulting in open surgical intervention
• Pregnancy
• Prisoners
• Active military
• Non - English speaking (due to necessity for consent in aims 2 and 3)
• Age > 89 years