Real-world Clinical Efficacy of Abatacept in the T3 Data Registry

Arthritis Northwest

Status: Completed

Conditions: Arthritis, Rheumatoid

Treatments: Drug: Abatacept

Study type: Observational

Funder types: Industry

Identifiers

NCT01555879

IM101-322

ANW_20110816 (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to assess the effectiveness of Abatacept in real-world clinical practice. The main hypothesis to be examined in this study is, "Abatacept's effectiveness results in a single real-world clinic (n = 100) are reproducible at another site (n ~= 200)".

Full description

Two secondary hypotheses that will be tested are:

• Abatacept aids in achieving low disease activity or clinical remission in patients of the following Rheumatoid Arthritis (RA) sub-groups: RF+/CCP+, RF+/CCP- RF-/CCP+ RF-/CCP-; first time on a bio-tech drug; having previously failed a biological drug; having interstitial lung disease; identified as disabled; twenty-eight individual joints identified as {swollen, painful, tender, deformed or having decreased range of motion}; on or not on oral DMARD; age; or gender.
• A database with sufficient attributes exists from which a patient's efficacy on abatacept is accurately predictable.

Enrollment: 200 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with rheumatoid arthritis
• Have used Abatacept for 3 or more months

Exclusion criteria

• None

Trial design

200 participants in 1 patient group

All patients

Description:

All patients in T3 who have used Abatacept for at least 3 months between 2009-03-17 and 2011-11-30.

Treatment:

Drug: Abatacept