Real-world Retrospective Data Analysis of Adjuvant Therapy for Patients With Stage II-III Colon Cancer After Radical Surgery

Zhejiang University

Status: Unknown

Conditions: Stage II Colon Cancer; Stage III Colon Cancer; Adjuvant Therapy

Study type: Observational

Funder types: Other

Identifiers

NCT03958435

REDUCE201809

Details and patient eligibility

About

Background:

1. . The incidence and mortality of colon cancer are high in China and in the world.
2. . The treatment of many patients in the real world is not standardized, and there are problems such as over-treatment or under-treatment. To explore the adjuvant treatment of colon cancer in the Chinese population, this study will retrospectively analyze real-world data on adjuvant therapy for colon cancer in Chinese patients after radical surgery.

The purpose of research:

1. . Current status of adjuvant therapy for stage II-III colon cancer in the real world: chemotherapy regimen, chemotherapy time, efficacy, safety, etc.
2. . Comparison of efficacy and safety of different adjuvant chemotherapy time (<3 months vs. >=3 months) in high-risk stage II and III colon cancer patients in the real world
3. . Comparison of efficacy and safety of different adjuvant chemotherapy regimens (XELOX vs. FOLFOX) in high-risk stage II and III colon cancer patients in the real world

Enrollment: 20,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who are sick after January 2010
• Age is older than 18
• Surgical pathology confirmed TNM stage II-III (AJCC 7th edition) colon cancer

Exclusion criteria

• Combine other tumors
• Pathological information is not clear
• Researchers believe that other reasons are not suitable for enrollment