Realistic Models of Gastrointestinal Bioelectromagnetism (SQUID)

Alan Bradshaw

Status: Completed

Conditions: Ischemia

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00178997

5R01DK064775 (U.S. NIH Grant/Contract)

040014

Details and patient eligibility

About

The purpose of this study is to look at the electrical activity present in healthy and diseased smooth muscle of the intestines; and develop both mathematical and computer models.

Full description

The Superconducting QUantum Interference Device (SQUID)is a large cylinder machine located in a large shielded room that measures magnetic activity of the intestines. Subjects will be asked to lie underneath and get recordings of the electrical activity of their intestines. They will also be asked to have a CT scan done. From these two procedures, the mathematical and computer models will be developed to determine the difference between normal bowels and those that do not have adequate blood supply.

Enrollment: 20 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal subjects and those with diseased bowel

Exclusion criteria

• Subjects with claustrophobia

Trial design

20 participants in 2 patient groups

Good blood flow

Description:

Group without ischemia to the small intestine

Poor blood flow

Description:

Groups that have partial ischemia to their small intestine