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Reboxetine Adjuvant Therapy for the Treatment of Schizophrenia

A

Abarbanel Mental Health Center

Status and phase

Unknown
Phase 1

Conditions

Schizophrenia

Treatments

Drug: reboxetine adjuvant therapy

Study type

Interventional

Funder types

Other

Identifiers

NCT00409201
284 (Other Identifier)

Details and patient eligibility

About

30 patients will randomly be selected and will be administered either reboxetine or a placebo. changes in cognition and behavior will be assessed by computer tests and scales during a six week study period.

Full description

all participants will be administered panss, sans, esrs, calgary, progesterom, sexual functioning scale, ham-a, covy, hamilton depression scale, and cgi and cgi improved rating on the first visit, as well as blood tests, ecg and weight. they will then be tested using a computer cognitive test (cogscan test) that lasts about 45 minutes. next, they will be given either a two week dose of placebo or treatment (2 mg * 2 daily for first week, then 4 mg. day, 2 mg. night for the second week). after two weeks they the dose is increased to 4 mg. * 2 daily. at four weeks all tests are readministered, as well as at six weeks. the study is concluded at 6 weeks, following a readministration of tests. physical examination is also administered at the conclusion.

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • schizophrenia all types
  • 18>

Exclusion criteria

  • uti
  • >65
  • non organic state
  • no depression treatment

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Single Group Assignment

Masking

Double Blind

Trial contacts and locations

1

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Central trial contact

stanislav baranchik, md

Data sourced from clinicaltrials.gov

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