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About
The LALGFA2019 Recommendations redefine the standard risk criteria and propose to introduce anthracycline induction in so-called high-risk forms (LAL line T and LAL line B with leukocytosis greater than or equal to 50 G/L or in children less than 1 year of age or more than 10 years of age) as well as Endoxan and Methotrexate in high dose consolidation.
Full description
A few studies conducted in developing countries confirm that it is possible to significantly improve the prognosis of children with Acute Lymphoblastic Leukemia (ALL) provided that the centres can benefit from a precise and adapted protocol and logistical support.
The GFAOP has been working with units for the past 20 years and this is the second study put in place by the group for the treatment of LAL. The initial study was a feasibility study with the treatment of standard risk LAL. This study GFALAL2019 aims to include both standard and high-risk forms of LAL.
With this study it is hoped to:
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
Children 0 to 18 ALL first diagnosis No prior chemotherapy Cytology FAB L1 or L2
Exclusion criteria
ALL L3 (Burkitt) ALL previously treated with chemotherapy Trisomy 21
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Central trial contact
BRENDA Ms MALLON, MSc; Ndella Ms DIOUF, MD
Data sourced from clinicaltrials.gov
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