Recovery After Laparoscopic Surgery

Herlev Hospital

Status: Completed

Conditions: Laparoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT01992640

11-2013

Details and patient eligibility

About

During laparoscopic surgery, muscle relaxants are often administrated in order to ensure acceptable surgical conditions. These drugs bind to receptors in the neuromuscular junction.

The degree of muscle relaxation is monitored by use of an acceleromyography and at the end of surgery another drug - Neostigmine- is given to reverse the muscle relaxation. However,there may still be a blockade of up to 70% of the receptors.

This partial muscle relaxation may result in muscle weakness, reduced balance and prolonged hospitalization.

This study will describe changes in balance and subjective muscle weakness after laparoscopic surgery.

The primary hypothesis is that sway area is increased 30 min after extubation compared to the preoperative value.

Enrollment: 25 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age above 18 years
• Same-day gynaecological laparoscopic surgery
• Informed consent

Exclusion criteria

• Body mass index above 30 kg/m2
• Insufficient renal function
• Liver insufficience
• Neuromuscular monitoring not possible
• Known allergy towards medicine used in the protocol
• Daily use of opioids
• Known disease which can interfere with the balance
• Pregnant/lactating
• Cannot read or understand danish
• Fast-track intubation with use of succinylcholine