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Recovery of Patients From COVID-19 After Critical Illness

A

Australian and New Zealand Intensive Care Research Centre

Status

Completed

Conditions

COVID-19
Critical Illness

Study type

Observational

Funder types

Other

Identifiers

NCT04401254
COVID-Recovery V1.5 9Feb2022

Details and patient eligibility

About

Patients who are critically ill with COVID-19 requiring life support in an intensive care unit (ICU) have increased risk of morbidity and mortality. Currently the ICU community does not know what effect the disease, the ICU admission, physiotherapy interventions and life support have on their long-term quality of life and whether they can return to their pre-illness level of function following ICU.

COVID-Recovery will describe the physiotherapy interventions delivered to critically ill patients with COVID-19. In survivors, COVID-Recovery will utilise telephone follow-up of ICU survivors to assess disability-free survival and quality of life at 6 months after ICU admission. Additionally, COVID-Recovery will identify if there are predictors of disability-free survival. COVID-Recovery will aim to select up to 300 patients diagnosed with COVID-19 from ICUs in Australia. If they survive to hospital discharge, patients will be invited to receive a telephone questionnaire at 6 months after the ICU admission that aims to assess their long-term outcomes, including physical, cognitive and emotional function, quality of life, and whether they have been able to return to work following ICU discharge.

To describe the experience of critical illness in survivors of COVID-19 and their family members.

To explore and describe functional recovery, respiratory system function and respiratory health morbidity up to 6 months after ICU admission in persistently critically ill adults with COVID-19

Enrollment

536 patients

Sex

All

Ages

17+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. COVID-19 patients who have been admitted to ICU for > 24 hours
  2. Patients aged over 17 years

Persistent critical illness cohort

  1. As above
  2. An ICU admission of at least 10 consecutive days

Exclusion criteria

  • Previous enrolment in this study in a prior ICU admission

Trial contacts and locations

29

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Data sourced from clinicaltrials.gov

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