Recovery of Short-term Renal Function in Post-transplant Patients Living Donor

Instituto Mexicano del Seguro Social

Status: Completed

Conditions: Nephrectomy

Treatments: Procedure: Laparoscopic nephrectomy; Procedure: Open nephrectomy; Procedure: Hand-assisted laparoscopic nephrectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT03717259

Post_transplant_2016

Details and patient eligibility

About

Objectives: To describe and analyze the perioperative and functional evolution of short-term renal graft in patients with kidney transplantation from a live donor, comparing three surgical techniques for obtaining kidney graft: open nephrectomy, laparoscopic hand-assisted nephrectomy, and pure laparoscopic nephrectomy.

Full description

Analytical cross-sectional study that will compare the three renal graft procurement techniques: open nephrectomy, laparoscopic hand-assisted nephrectomy, and pure laparoscopic nephrectomy. The investigators will analyze serum creatinine values on days 1, 5 and 28 post renal transplantation. The operative, medical and surgical morbidity will also be evaluated, considering the bleeding in the donor, times of ischemia and the need for JJ catheter placement in the recipient.

Enrollment: 508 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with terminal chronic kidney disease who will receive a kidney transplant in the transplant service of the National Medical Center of the West of living donor related to the means of obtaining the kidney graft by laparoscopic hand assisted or pure laparoscopic surgery.

Exclusion criteria

• Patients who for some reason can not find your complete medical record.
• Patients obtained a kidney graft from a brain death donor.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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508 participants in 3 patient groups

Open nephrectomy

Active Comparator group

Description:

These patients will undergo an open nephrectomy.

Treatment:

Procedure: Open nephrectomy

Hand-assisted laparoscopic nephrectomy

Active Comparator group

Description:

These patients will undergo a hand-assisted nephrectomy.

Treatment:

Procedure: Hand-assisted laparoscopic nephrectomy

Laparoscopic nephrectomy

Active Comparator group

Description:

These patients will undergo a pure laparoscopic nephrectomy.

Treatment:

Procedure: Laparoscopic nephrectomy