Recruitment Maneuver After Bronchoalveolar Lavage in ARDS Patients

Southeast University, China

Status: Not yet enrolling

Conditions: Acute Respiratory Distress Syndrome

Treatments: Other: Recruitment Maneuver

Study type: Interventional

Funder types: Other

Identifiers

NCT05372731

BAL20220420

Details and patient eligibility

About

ARDS caused by pneumonia is one of the main reasons for ICU admission in critically ill patients, and also a common complication in patients admitted to ICU with invasive mechanical ventilation. Bronchoalveolar lavage (BAL) is the main diagnostic method for these patients, which often leads to alveolar collapse and exacerbates hypoxemia. In clinical practice, recruitment maneuver (RM) is often used immediately after BAL to prevent such a situation, but there is a lack of data on RM after BAL.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Adult patients with invasive mechanical ventilation;
2. Patients who diagnosed with ARDS according to the Berlin definition
3. There are indications for bronchoalveolar lavage

Exclusion criteria

1. Patients with contraindications for EIT procedures;
2. Patients with contraindications for RM;
3. Previous chronic respiratory diseases (long-term home oxygen therapy for chronic respiratory diseases such as pulmonary fibrosis or COPD);
4. Pregnancy;
5. Refusal to sign informed consent

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

RM after BAL

Experimental group

Description:

patients underwent RM after BAL

Treatment:

Other: Recruitment Maneuver

Non-RM after BAL

No Intervention group

Description:

patients did not undergo RM after BAL