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Effect of Rectus Sheath Block on Diaphragmatic Function After Elective Upper Abdominal Surgery

A

Assiut University

Status

Enrolling

Conditions

Acute Pain

Treatments

Procedure: Rectus Sheath Block

Study type

Interventional

Funder types

Other

Identifiers

NCT03725527
17100594

Details and patient eligibility

About

This study will be undertaken to investigate the respiratory and analgesic effects of ultrasound guided rectus sheath block analgesia after elective abdominal surgery with midline incision.

Full description

A major proportion of pain experienced by patients undergoing abdominal surgeries is due to somatic pain signals derived from the abdominal wall. The central portion of anterior abdominal wall components (skin, muscles and parietal peritoneum) is innervated by sensory neurons branching from the anterior rami of spinal nerves T7 to T1. These neurons lie between the rectus abdominis muscle and posterior rectus sheath, and pierce the rectus muscle close to the midline. The tendinous intersections of the rectus muscle do not fuse with the posterior rectus sheath, thereby allowing the injectate to spread cephalo-caudally within this potential space. Rectus sheath (RS) block has been described for any midline abdominal incisions (epigastric and umbilical hernia repairs). As visceral pain becomes attenuated by the 2nd postoperative day, rectus sheath block can also be administered for midline laparotomy.

However, the effects of rectus sheath block analgesia on the respiratory function after abdominal surgery with midline incisions are still under investigation.

Enrollment

60 estimated patients

Sex

All

Ages

18 to 50 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age: 18-50 years.
  • Sex: both males and females.
  • BMI< 30kg/m2.
  • ASA physical status: 1, II and III.
  • Elective abdominal surgery with midline incisions.

Exclusion criteria

  • Patient refusal.
  • Infection at injection site
  • Coagulation disorders.
  • Allergy to study medications.
  • Pregnancy.
  • Respiratory tract infection within the last 2 weeks.
  • Urgent abdominal surgery

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

60 participants in 2 patient groups

Rectus sheath block
Active Comparator group
Description:
Patients will receive ultrasound-guided rectus sheath block' performed after induction of general anesthesia and before surgery.
Treatment:
Procedure: Rectus Sheath Block
control
No Intervention group
Description:
Patients will receive general anesthesia .

Trial contacts and locations

1

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Central trial contact

Beshoy B Bolis, MBBCH; Noha Y Mohamed, MD

Data sourced from clinicaltrials.gov

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