Recurrence of H Pylori : Incidence and Influential Factors.

Sohag University

Status

Enrolling

Conditions

H. Pylori Infection

Treatments

Behavioral: follow up of patients that had H. Pylori infection and recieved medical treatment for recurrence

Study type

Interventional

Funder types

Other

Identifiers

NCT07045857

Soh-Med--25-5-11MS

Details and patient eligibility

About

This study aims to determine recurrence rates, identify influential factors, investigate key factors that contribute to recurrence, evaluate treatment effectiveness and to assess the efficacy of different eradication regimens and their role in reducing recurrence.

Enrollment

100 estimated patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age: 18-75 years old.
H. pylori infection: Confirmed by endoscopy, biopsy, or non-invasive tests (e.g., urea breath test, stool antigen test).
Symptoms: Presence of dyspepsia, peptic ulcer disease, or other H. pylori-related symptoms.
Laboratory tests: Normal liver and kidney function, and no significant abnormalities in blood counts.

Exclusion criteria

Patients receiving eradication therapy in the past taking proton pump inhibitors,, H2 blockers ,,bismuth ,, antibiotics or other medications that interfere with the result of the examination in the recent 4 weeks.
Gastrointestinal disorders: Severe gastrointestinal disorders (e.g., gastric cancer, inflammatory bowel disease ,gastric or duodenal ulcer with current or recent bleeding , or clinical significant gastrointestinal bleeding within 4 weeks of randomization).
Malignancies: Active or recent malignancies.
Severe comorbidities: Unstable or severe comorbidities (e.g., heart failure, liver cirrhosis).