Recurrence Rate, Risk Factors for the Recurrence, and Quality of Life in Patients With GERD in Korea-an Observational (Refresh)

AstraZeneca

Status: Completed

Conditions: The Aim of This Study is to Investigate the Frequency and Related Risk Factors of Recurrence, and Quality of Life in Patients With GERD After Treatment With PPI

Study type: Observational

Funder types: Industry

Identifiers

NCT01378338

NIS-GKR-ATC-2011/1

Details and patient eligibility

About

Recurrence rate, risk factors for the recurrence, and quality of life in patients with GERD in Korea-an observational study.

Enrollment: 855 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Both ERD or NERD patient who confirmed by EGD findings within 12 months prior to V1 and have a symptom with moderate or more, at least once per week within 1 week prior to V1 and Patients between age 20 and 80with typical reflux symptoms
• Among the patient who have not taken PPI or H2 blocker within 4 weeks prior to V1, needs to be prescribed PPIs 4~8 weeks as a part of the routine clinical practice due to typical symptom
• Patients who give the signed informed consent

Exclusion criteria

• Patients with past history of gastrointestinal surgery
• Patients with known malignancy or history of such diseases
• Patients with moderate to severe general medical conditions like ischemic heart disease, chronic renal failure, congestive heart failure, COPD, liver cirrhosis, acute or chronic pancreatitis, or other medical conditions which the investigator considers

Trial design

855 participants in 1 patient group

Typical reflux symptom by EGD

Description:

Total 2000 subjects who has Typical reflux symptom by EGD