Recurrent Campylobacter Bacteraemia in Immunocompromised Patients (CABARET)

Civil Hospices of Lyon

Status: Not yet enrolling

Conditions: Campylobacter Infections

Treatments: Other: Characteristics of patients and Campylobacter bacteraemia episodes

Study type: Observational

Funder types: Other

Identifiers

NCT06432777

69HCL24_0512

Details and patient eligibility

About

Some rare cases of recurrent Campylobacter bacteraemia (RCB) exist with relapses months to years after an effective treatment and a negativation of all bacterial samples.

As of today, only around 20 cases have been described in the international literature for the last 30 years. The cases are likely highly underreported.

No study describes those recurrent Campylobacter bacteraemias at the scale of a country.

The aim of this multicentre, nationwide, retrospective study is to describe their precise epidemiology in France for the last 25 years, the immune profile of the patients, the specificities of the bacteria involved, the treatments received and the evolution of these infections.

The perspective is to propose a standardization of the medical care of those patients mainly by describing the effective treatments and the explorations of the immune system which should be considered.

Enrollment: 30 estimated patients

Sex: All

Ages: Under 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 2 episodes or more of Campylobacter bacteraemia separated by at least 60 days
• AND immunodeficiency condition
• followed by a French hospital

Exclusion criteria

-Opposition of the patient

Trial design

30 participants in 1 patient group

Recurrent Campylobacter bacteraemia

Description:

Patients presenting at least two distinct episodes of Campylobacter bacteraemia separated by minimum 60 days and an immunodeficiency (innate or acquired) and followed by a French hospital

Treatment:

Other: Characteristics of patients and Campylobacter bacteraemia episodes