Recurrent Laryngeal Nerve's Motor Function: Sometimes Motor Fibers May Also Be Located in The Posterior Branch

Sisli Hamidiye Etfal Training and Research Hospital

Status: Completed

Conditions: Recurrent Laryngeal Nerve Injuries

Treatments: Device: intraoperative neuromonitoring

Study type: Interventional

Funder types: Other

Identifiers

NCT02493881

SEEAH01

Details and patient eligibility

About

The investigators hypothesized that, sometimes the posterior branch of the recurrent laryngeal nerve may also have motor function. The investigators aimed to evaluate motor function of the branches in the branching recurrent laryngeal nerves in this study.

Full description

This study group consisted of consecutive patients, undergoing thyroid and parathyroid surgery with IONM. Both anterior and posterior branches of the recurrent laryngeal nerves were assessed separately by both electromyography endotracheal tube for adduction and finger palpation for detection of laryngeal twitch due to posterior cricoarytenoid abduction. The recurrent laryngeal nerves having motor function only in the anterior branches were defined as group 1, whereas the nerves having motor function both in the anterior and posterior branches were as group 2.

Enrollment: 337 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients who underwent parathyroid/thyroid surgery with intraoperative neuromonitoring ,
2. Patients who had normal vocal cord functions preoperatively. -

Exclusion criteria

1. Preoperative recurrent laryngeal nerve palsy,

2. Intentional nerve transection because of cancer invasion,

3. Assessment failure of recurrent laryngeal nerve function due to the deficiency of the intraoperative neuromonitoring equipment,.

4. Parathyroidectomy operations that recurrent laryngeal nerves were not fully dissected.

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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337 participants in 2 patient groups

Group 1

Active Comparator group

Description:

The RLNs having motor function on the anterior branch assessed by intraoperative neuromonitoring.

Treatment:

Device: intraoperative neuromonitoring

Group 2

Active Comparator group

Description:

RLNs having motor function on anterior and posterior branch assessed by intraoperative neuromonitoring.

Treatment:

Device: intraoperative neuromonitoring