Red Cell Distribution Width,,NT-proBNP and cTnT in Acute Myocardial Infraction Patient

Sohag University

Status: Not yet enrolling

Conditions: Myocardial Infarction

Treatments: Diagnostic Test: (CBC) ,(NT-proBNP) ,(cTnT)

Study type: Observational

Funder types: Other

Identifiers

NCT05595278

Soh-Med-2210-05

Details and patient eligibility

About

the study is to investigate the relationship of several parameters of complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.

Full description

Patients and methods:

• Type of study: Observational prospective study

• Place of study: Sohag cardiology and gastroenterology center, department of cardiology and cardiac care unit.

• Ethical considerations: This research will be revised by the Scientific Ethical Committee of Sohag University Hospital. Consents will be taken from all patients.

• Study Methods:

  • A prospective study on 30 patients diagnosed as acute myocardial infarction on which measurement of CBC, serum NT-proBNP, and cTnT levels will be performed at the time of admission and by the time of discharge.

  • All patients included in the study will be subjected to:

    1. Full history:

       1. Personal history: e.g. age, sex and smoking.
       2. Family history of cardiac diseases
       3. Medical history of: Hypertension, Ischemic heart disease, prior coronary artery bypass grafting, Prior Percutaneous coronary intervention, Prior Stroke, Prior Atrial fibrillation, therapeutic history

    2. Detailed clinical examination

    3. Electrocardiogram

    4. Laboratory investigation:

       1. Routine investigation in the form of CBC including RDW
       2. Specific investigation which include NT-proBNP and cTnT

Enrollment: 30 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients diagnosed as acute myocardial infarction and admitted to department of cardiology and cardiac care unit at Sohag cardiology and gastroenterology center according to inclusion and exclution criteria

Exclusion criteria

Patient with:

• Decompensated heart failure
• Pulmonary hypertention
• Acute pulmonary embolism
• Septic shock