Red Yeast Rice and Subclinical Atherosclerosis in Patients With Rheumatoid Arthritis

Chengdu PLA General Hospital

Status: Unknown

Conditions: Rheumatoid Arthritis

Treatments: Dietary Supplement: RYR; Dietary Supplement: Tea

Study type: Interventional

Funder types: Other

Identifiers

NCT02257047

RYR20140104

Details and patient eligibility

About

To evaluate the effect of red yeast rice on subclinical atherosclerosis in patients with rheumatoid arthritis

Enrollment: 120 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with a definite diagnose of rheumatoid arthritis(RA) were included if they met the classification criteria for RA established by the American Rheumatism Association (ACR) and European League Against Rheumatism (EULAR) in 2010
• aged from 18 to 75 years
• without conflict to the written, informed consent signed prior to the enrollment
• no severe hepatic or renal disorders
• no known carotid artery stenosis
• no coagulation disorders
• no hypertension

Exclusion criteria

• being in pregnancy, lactation period or under a pregnancy plan
• being allergic to the test drug
• not compatible for the trial medication
• without full legal capacity

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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120 participants in 2 patient groups

RYR

Experimental group

Description:

Patients under the treatment of red yeast rice

Treatment:

Dietary Supplement: RYR

Control

Sham Comparator group

Description:

Patients under the treatment of tea

Treatment:

Dietary Supplement: Tea