Reducing and Removing Hyaluronic Acid Filler with Hyaluronidase

Northwestern University

Status and phase: Active, not recruiting; Early Phase 1

Conditions: Drug Safety

Treatments: Drug: Hyaluronidase

Study type: Interventional

Funder types: Other

Identifiers

NCT01722916

STU68166

Details and patient eligibility

About

The purpose of this study is to find how much hyaluronidase should be used when receiving injections of fillers.

Enrollment: 5 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18 and over
• The subjects are in good health
• The subject has the willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator

Exclusion criteria

• Under 18 years of age
• Pregnancy or Lactation
• Subjects who are unable to understand the protocol or to give informed consent
• Subjects with mental illness
• Recent Accutane use in the past 6 months
• Subjects prone to hypertrophic and keloidal scarring
• Subjects with tattoos and/or scars on upper medial arms (the treatment area)
• Subjects with known hypersensitivity to hyaluronic acid

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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5 participants in 1 patient group

Dose of Hyaluronidase

Experimental group

Treatment:

Drug: Hyaluronidase