Reducing Mesh Infections in Open Hernia Repairs

University of Saskatchewan

Status and phase: Unknown; Phase 3; Phase 2

Conditions: Patients Undergoing Ventral or Inguinal Hernia Repair; Patients Undergoing Open Hernia Repair

Treatments: Procedure: vancomycin-soaked mesh; Procedure: plain mesh

Study type: Interventional

Funder types: Other

Identifiers

NCT01860469

MeshVanco

Details and patient eligibility

About

Soaking meshes in a vancomycin solution just prior to their use in open hernia repairs will decrease rates of mesh infection

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• open ventral or inguinal hernia repair

Exclusion criteria

• laparoscopic hernia repair
• non ventral or inguinal hernia repairs

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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0 participants in 2 patient groups

plain mesh

Active Comparator group

Description:

standard practice of using plain mesh (non vancomycin-soaked) for open hernia repair

Treatment:

Procedure: plain mesh

vancomycin-soaked mesh

Experimental group

Description:

use of vancomycin-soaked mesh for open hernia repair

Treatment:

Procedure: vancomycin-soaked mesh